Description
A selective and reversible MAO-A inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively); selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively); reverses the depressive-like effects induced by CMS, increases hippocampal cell proliferation, and reverses CMS-induced dendritic atrophy in granule neurons in rats; inhibits enterovirus-D68 and CV-B3; inhibits CV-B3 genome replication (EC50 = 7.7 µM)