Description
A sesquiterpene; inhibits CYP2C9 (Ki = 1.26 µM); reduces Pck1 and G6pc gene expression, cAMP concentration, and CREB phosphorylation, increases PDE3 activity, and inhibits gluconeogenesis in rat primary hepatocytes; decreases serum and hepatic triglyceride levels, as well as random-fed and fasting blood glucose levels in ob/ob mice