Description
A positive allosteric modulator of δ-opioid receptors; has an average EC50 value of 30 nM for β-arrestin recruitment in the presence of the endogenous δ-opioid receptor agonist leu-enkephalin, but little to no activity in the absence of an agonist; 100-fold selective for δ- over µ-opioid receptors in the presence of endogenous ligands