OSMI-1 from Cayman Chemical

Product Specs
ItemOSMI-1
CompanyCayman Chemical
Price $160.00Supplier Page View Company Product Page
Catalog Number21894
FormatA crystalline solid
Molecular Weight563.6
Quantity5 mg
Purity≥98%
TypeInhibitors
OriginUSA
FormulaC28H25N3O6S2
Storage-20

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Site-specific glycosylation of Sec24D and myoferlin recruit ERGIC to ER exit sites for collagen traffickingNature CommunicationsMay 13, 2026Tetsuya Hirata, Dharmendra Choudhary, Quyen Nguyen, Brittany J. Bisnett, Erik J. Soderblom, Ela W. Knapik, Michael Boycepretreatment, cells incubated at 40 °C for 1 h were treated with 20 µM OSMI-1 (OGT inhibitor, Cayman Chemical #21894) for 2 h at 40 °C and were used in subsequent IB and collagen transport experiments. siRNA transfection Cells

(2) Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesisCell Chem BiolFebruary 19, 2026Peter Geon Kim, Christopher B Hergott, Aidan P Miller, Amy Deik, Meaghan Boileau, Kevin Bullock, Kerry A. Pierce, Angelina H. Choy, Wesley Shin, Marie McConkey, et al.concentrations of glucose was added. For drug treatments, the following drugs were used OSMI1 (Cayman Chemical 21894), 16,16-dimethylPGE2 (Cayman Chemical 14750), (Z)-PUGNAc (Cayman Chemical 17151), doxycycline (Selleck Chemicals

(3) Evidence for functional regulation of the KLHL3/WNK pathway by O-GlcNAcylationGlycobiologyAugust 11, 2025Jimin Hu, Duc T. Huynh, Denise E. Dunn, Jianli Wu, Cindy Manriquez-Rodriguez, Qianyi E. Zhang, Gabrielle A. Hirschkorn, Tetsuya Hirata, George R. Georgiou, Samuel A. Myers, et al.Chemical name,Vendor and catalog number Thiamet-G,"Cayman, 13237" OSMI-1,"Cayman, 21894" Erastin,"Sigma, 329600" ZT-1a,"MedChemExpress, HY-136532" WNK463,"Sigma, SML2809" Fer-1,"Cayman,

(4) Glucose Metabolism Sustains Aberrant STAT3 Signaling in Colorectal Cancer via Glycosylated Paracrine FactorsbioRxiv : the preprint server for biologyJuly 26, 2025Buscher K, Temprine K, Mays C, Aabed N, Kerk S, Bell HN, Nieto Carrion JA, Greenbaum H, Ponnusamy V, Ramakrishnan SK, et al.Glycosylation was inhibited using 1 or 10μM NGI-1 (MedChem Express, HY-117383) or 50μM OSMI-1 (Cayman Chemical, 21894) for 24 hours. Cells were treated with 5, 15, or 30μM SBC-115076 (PCSK9 inhibitor; MedChem Express HY-12402)

(5) Evidence for Functional Regulation of the KLHL3/WNK Pathway by O-GlcNAcylationbioRxivMarch 1, 2025Jimin Hu, Duc T. Huynh, Denise E. Dunn, Jijanli We, Cindy Manriquez-Rodriguez, Qianyi E. Zhang, Gabrielle A. Hirschkorn, George R. Georgiou, Tetsuya Hirata, Samuel A. Myers, et al.Chemical name,Vendor and catalog number Thiamet-G,"Cayman, 13237" OSMI-1,"Cayman, 21894" Erastin,"Sigma, 329600" ZT-1a,"MedChemExpress, HY-136532" WNK463,"Sigma, SML2809" Fer-1,"Cayman,

(6) Overexpression of Fatty Acid Synthase Upregulates Glutamine–Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer GrowthInternational Journal of Molecular SciencesApril 30, 2024James Drury, Mariah E. Geisen, Josiane Weber Tessmann, Piotr G. Rychahou, Courtney O. Kelson, Daheng He, Chi Wang, B. Mark Evers, Yekaterina Y. ZaytsevaHT29 cells. The next day, cells were treated with different concentrations of azaserine (#14834) and OSMI-1 (#21894) inhibitors (Cayman Chemical, Ann Arbor, MI, USA). After 48 h treatment, cells were trypsinized, collected

(7) Critical Role of Novel O-GlcNAcylation of S550 and S551 on the p65 Subunit of NF-κB in Pancreatic CancerCancersSeptember 27, 2023Motolani A, Martin M, Wang B, Jiang G, Alipourgivi F, Huang X, Safa A, Liu Y, Lu T.control or FLAG-WT-p65 stable cell lines. Cells were treated with or without OSMI-1 (Cayman chemical, 21894-1, Ann Arbor, MI, USA) for 24 h. Luciferase activity was quantified 48 h after transfection using the

(8) Inhibition of O-GlcNAcylation protects from Shiga toxin-mediated cell injury and lethality in hostEMBO molecular medicineJanuary 11, 2022Lee KS, Lee J, Lee P, Jeon BC, Song MY, Kwak S, Lee J, Kim JS, Kim DJ, Kim JH, et al.Falmouth, MA, USA). OSMI‐1 was initially purchased from Sigma (SML 1621) and subsequently from Cayman (21894), and Retro‐2 was from Sigma (SML 1085). MKC‐3946 (HY‐19710) and Thiamet G (HY‐12588) were purchased

(9) Sex alters thyroid hormone's effect on protein O-GlcNAcylation in the aged mouse heartBMC molecular and cell biologyJanuary 1, 0001"Olson AK, Zhu WZ, Ledee D."MilliporeSigma, St.Louis, MO), ± 20 µM thiamet G (#13237, Cayman Chemical, Ann Arbor, MI), ± 25 µM OSMI-1 (#21894, Cayman Chemical, Ann Arbor, MI) for 24 h before assay. Luciferase activity was assessed using the Dual-Glo Luciferase assay system

(10) Mitochondrial Protein Poldip2 (Polymerase Delta Interacting Protein 2) Controls Vascular Smooth Muscle Differentiated Phenotype by O-Linked GlcNAc (N-Acetylglucosamine) Transferase-Dependent Inhibition of a Ubiquitin Proteasome SystemCirculation researchJanuary 1, 0001"Paredes F, Williams HC, Quintana RA, San Martin A."made available on request. General Reagents MG132, Azaserine, and Osmi (Cayman, 13697, 14834, and 21894), Cycloheximide (Sigma, C1988), Bz-Val-Gly-Arg-AMC (Enzo Life Sciences, BML-BW9375-0005), Recombinant human

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OSMI-1 from Cayman Chemical

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Cayman Chemical

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OSMI-1 from Cayman Chemical

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