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Protein Biochemistry
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RY785
RY785 from Cayman Chemical
Be the first to write a review!
Citations:
(4)
Supplier Page
Supplier Page from
Cayman Chemical for
RY785
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Description
A selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 µM)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
RY785
Company
Cayman Chemical
Price
$333.00
Supplier Page
View Company Product Page
Catalog Number
19813
Format
A crystalline solid
Molecular Weight
392.5
Quantity
5 mg
Purity
≥98%
Type
Inhibitors
Origin
USA
Formula
C21H20N4O2S
Storage
-20
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (4)
(1)
A Kv2 inhibitor combination reveals native neuronal conductances consistent with Kv2/KvS heteromers
Elife
May 27, 2025
Robert G Stewart, Matthew James Marquis, Sooyeon Jo, Brandon J Harris, Aman S Aberra, Verity Cook, Zachary Whiddon, Vladimir Yarov-Yarovoy, Michael Ferns, Jon T Sack
cells were held at a
membrane
potential of –89 mV. RY785 (gift from Bruce Bean, Harvard, or
Cayman
,
19813
) was prepared in DMSO as a 1 mM stock for dilutions to 1 µM or a 35 mM stock for concentration-effect
(2)
A Kv2 inhibitor combination reveals native neuronal conductances consistent with Kv2/KvS heteromers
Elife
May 27, 2025
Robert G Stewart, Matthew James Marquis, Sooyeon Jo, Brandon J Harris, Aman S Aberra, Verity Cook, Zachary Whiddon, Vladimir Yarov-Yarovoy, Michael Ferns, Jon T Sack
cells were held at a
membrane
potential of –89 mV. RY785 (gift from Bruce Bean, Harvard, or
Cayman
,
19813
) was prepared in DMSO as a 1 mM stock for dilutions to 1 µM or a 35 mM stock for concentration-effect
(3)
Electrically silent KvS subunits associate with native Kv2 channels in brain and impact diverse properties of channel function
bioRxiv
February 6, 2024
Michael Ferns, Deborah van der List, Nicholas C. Vierra, Taylor Lacey, Karl Murray, Michael Kirmiz, Robert G. Stewart, Jon T. Sack, James S. Trimmer
protocols while
neurons
were held at a
membrane
potential of −80 mV. A stock
of 1
mM
RY785
(
Cayman
Cat#
19813
) in 10% DMSO which had been stored at −20 °C was kept on ice and diluted in room temperature (20–22°C)
(4)
Mechanism of use-dependent Kv2 channel inhibition by RY785
Journal of General Physiology
June 6, 2022
Matthew James Marquis, Jon T. Sack
solution was supplemented with
1:1,000
vol:vol DMSO as a vehicle control or, when indicated, 1 µM
RY785
(
19813
;
Cayman
) as
1:1,000
1 mM
RY785
in DMSO. In some experiments, 5 µM tetrodotoxin was added to suppress
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RY785 from Cayman Chemical
Supplier Page
View Company Product Page
$333.00
Product Specs
Company Info
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