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Protein Biochemistry
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Chk2 Inhibitor II
Chk2 Inhibitor II from Cayman Chemical
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Citations:
(3)
Supplier Page
Supplier Page from
Cayman Chemical for
Chk2 Inhibitor II
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Description
A selective, ATP-competitive inhibitor of the DNA damage control kinase, Chk2 (IC50 = 15 nM); prevents apoptosis in human T-cells exposed to ionizing radiation (EC50 = 3-7.6 µM)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Chk2 Inhibitor II
Company
Cayman Chemical
Price
$103.00
Supplier Page
View Company Product Page
Catalog Number
17552
Format
A crystalline solid
Research Area
Cancer, Cell Biology, Cell Cycle, Cell Signaling, DNA Damage and Repair
Molecular Weight
363.8
Quantity
5 mg
Purity
≥98%
Storage
-20
Formula
C20H14ClN3O2
Origin
USA
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
Inhibition of nucleolar transcription by oxaliplatin involves ATM/ATR kinase signaling
Cell chemical biology
August 17, 2023
Nechay M, Wang D, Kleiner RE.
17921
GDC-0575
,
Cayman Chemical
,Cat# 34300 AZD7762,
Cayman Chemical
,Cat#
11491
BML-277,
Cayman Chemical
,Cat#
17552
VE-821
,Sigma-Aldrich,Cat# SML1415 KU-55933,Sigma-Aldrich,Cat# SML1109
Cisplatin
,
Sigma-Aldrich
,Cat#
(2)
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation
eLife
April 23, 2021
Sanders DW, Jumper CC, Ackerman PJ, Bracha D, Donlic A, Kim H, Kenney D, Castello-Serrano I, Suzuki S, Tamura T,
et al
.
hydrochloride,ApexBio,B6936, "Chemical compound, drug",
Avanafil
,
Cayman
,
23024
, "Chemical compound, drug",BML-277,
Cayman
,
17552
, "Chemical compound, drug",
Canagliflozin
,
Cayman
,
11575
, "Chemical compound, drug",Chlorohexidine,Targetmol,T1147, "Chemical
(3)
Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest
Oncogenesis
March 13, 2020
Marijn T. M. van Jaarsveld, Difan Deng, Diana Ordoñez-Rueda, Malte Paulsen, Erik A. C. Wiemer, Zhike Zi
treated with DMSO, CHK1 (PF477736,
Sigma-Aldrich
#PZ0186; 1 µM), or
CHK2 inhibitor
(
Cayman Chemicals
#
17552
; 10 µM) for 16 h. During the last 2 h, cells were incubated in the presence of 10 μM EdU. Depicted is
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Chk2 Inhibitor II from Cayman Chemical
Supplier Page
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$103.00
Product Specs
Company Info
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