Description
An agonist of 5-HT1B and 5-HT1D receptors (IC50s = 9.3 and 7.3 nM, respectively); binds to the 5-HT1F receptor (IC50 = 17.8 nM); induces vasoconstriction in isolated human middle meningeal arteries (EC50 = 89.9 nM); reduces acute, but not chronic, mechanical hyperalgesia in a mouse model of nitroglycerin-induced pain