Description
An anti-inflammatory, antimalarial, and antibacterial compound; reduces epidermal hyperproliferation and epithelial thickness in the esophagus in a mouse model of proliferative dermatitis when administered at a dose of 34 µg/animal per day; reduces lipid peroxidation, myeloperoxidase activity, and cellular apoptosis in the striatum of rats following ischemia and reperfusion injury; reduces growth of M. leprae in the footpad of mice (MIC = 0.01-0.03 µg/ml in sera); induces clearance of P. knowlesi infections in macaques; reduces the number of P. gallinaceum sporozoites in a mosquito population allowed to feed on dapsone-treated chicks