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STAT5 Inhibitor
STAT5 Inhibitor from Cayman Chemical
Be the first to write a review!
Citations:
(5)
Supplier Page
Supplier Page from
Cayman Chemical for
STAT5 Inhibitor
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Description
A cell-permeable, nonpetidic nicotinoyl hydrazone that selectively suppresses STAT5 by targeting its SH2 domain (IC50 = 47 µM against STAT5β SH2 domain EPO peptide binding activity)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
STAT5 Inhibitor
Company
Cayman Chemical
Price
$75.00
Supplier Page
View Company Product Page
Catalog Number
15784
Format
A crystalline solid
Research Area
Cancer, Epigenetics, Transcription, & Translation, Transcription Factors
Molecular Weight
293.3
Quantity
5 mg
Purity
≥95%
Storage
-20
Formula
C16H11N3O3
Origin
USA
Type
Inhibitors
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (5)
(1)
Osteocyte-derived erythroferrone regulates liver hepcidin during stress erythropoiesis∗
Blood Advances
April 14, 2026
Vamsee Dhar Myneni, Abhinav Parashar, Lynn Vitale-Cross, Ildiko Szalayova, Luis Fernandez de Castro, Eva Mezey
2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide-3-pyridine carboxylic acid] (200μM,
Cayman Chemical
; catalog no.
15784
). Next, the pretreated OEBTs were stimulated with 10 U/mL EPO, and after 16 hours, the tubes were collected
(2)
Antipsychotic Chlorpromazine Suppresses STAT5 Signaling, Overcomes Resistance Mediated by the Gatekeeper Mutation FLT3-ITD/F691L, and Synergizes with Quizartinib in FLT3-ITD-Positive Cells
Current Issues in Molecular Biology
September 25, 2025
Aki Fujii-Hanamoto, Hirokazu Tanaka, Ko Fujimoto, Takahiro Haeno, Yoshiaki Miyake, Ryosuke Fujiwara, Takahiro Kumode, Kentaro Serizawa, Yasuyoshi Morita, Hitoshi Hanamoto,
et al.
(Abs) CPZ and Quiz were purchased from
Sigma-Aldrich
(St. Louis, MO, USA). A
STAT5 inhibitor
(Item No.
15784
) was purchased from
Cayman Chemical
(Ann Arbor, MI, USA). These compounds were dissolved in distilled
(3)
Aging-associated HELIOS deficiency in naive CD4(+) T cells alters chromatin remodeling and promotes effector cell responses
Nature immunology
January 1, 2023
Zhang H, Jadhav RR, Cao W, Goronzy IN, Zhao TV, Jin J, Ohtsuki S, Hu Z, Morales J, Greenleaf WJ,
et al
.
PBS, 5 μg/mL αCD25 and αCD122 Ab, DMSO solvent control or 50 μM
STAT5 inhibitor
(
Cayman Chemical
, #
15784
) in DMSO. For experiments not involving genome-wide
sequencing
, samples were obtained from
leukocyte
(4)
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function
Platelets
April 3, 2022
Parra-Izquierdo I, Melrose AR, Pang J, Lakshmanan HHS, Reitsma SE, Vavilapalli SH, Larson MK, Shatzel JJ, McCarty OJT, Aslan JE.
upadacitinib (S8162) and oclacitinib (
S8195
) were from
Selleck Chemicals
(Houston, TX, USA).
STAT5 inhibitor
(
15784
) was from
Cayman Chemical Company
.
PP2
(
1407
) and Ro 31–8220 (2002) were from
Tocris
(Bristol, UK).
Platelet
(5)
IL-17
+
CD8
+
T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis
Nature communications
December 16, 2019
Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang Y, Klein M, Bittner S, Steffen F, Moos S,
et al
.
04876, 15 nM) Akt1/2inhibitor (Akti, Merck
Milipore
,
124018
, 1 µM),
STAT5 inhibitor
(STAT5i,
Cayman
,
15784
, 35 µM),
Ly294002
(
Cell Signaling
,
9901
, 1 µM), TSA (
Sigma-Aldrich
,
T8552
, 1 nM) and rapamycin (
Cell Signaling
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STAT5 Inhibitor from Cayman Chemical
Supplier Page
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$75.00
Product Specs
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