Description
An inhibitor of the amphiphysin-clathrin interaction (IC50 = 12 µM); inhibits clathrin-mediated transferrin uptake in HeLa and U2OS cells (IC50s = 12-15 and 9.7 µM, respectively); inhibits HIV-1 entry and infectivity in HeLa reporter cell lines; inhibits clathrin-independent endocytosis of CD44, CD98, and CD147 in HeLa cells