Description
An anticancer flavonol; decreases proliferation in K562, HL-60, and Kasumi-1 leukemia cells lines (IC50s = 5.95, 4.82, and 15.56 µM, respectively); blocks TGF-β/SMAD signaling in LX2 cells; decreases TGF-β1 mRNA and p-SMAD levels in a mouse model of liver fibrosis at a dose of 20 mg/kg; downregulates Twist and prevents EMT in HCC cells