Description
An inhibitor of AIFM2/FSP1; decreases cell viability in wild-type, but not GPX4 knock-out, Pfa1 and HT1080 cells overexpressing AIFM2/FSP1, an effect that can be blocked by liproxstatin-1; sensitizes a variety of human cancer cell lines to (1S,3R)-RSL3 at 3 µM