Welcome Guest
Sign In
Register
Products
Popular Categories
Antibody Search
ELISA Kit Search
Biomolecules
Flow Cytometers
Thermal Cyclers
Microscopes
Transfection Reagents
Featured Products
New Products
Research Areas
ELISA
Western Blot
3D Cell Culture
Digital PCR
Quantitative PCR
Cell and Gene Therapy
In Vivo Models
Resources
eBooks
Bench Tips
Tech Insights
Editorial Articles
News
Product Reviews
Future Lab
White Papers
Infographics
Events
Promotions
Multimedia
Biocompare Webinars
Technologies Transforming Precision Medicine
Immunotherapy
Reproducibility
Transformative Technologies
Podcasts
Bench Tip Videos
All Videos and Webinars
Life Science Webinars
Write a Review
Antibodies
Kits/Reagents
Equipment
Services
Register
Sign In
Biocompare
Products
Protein Biochemistry
Chemicals and Reagents
ZCL 278
ZCL 278 from Cayman Chemical
Be the first to write a review!
Citations:
(4)
Supplier Page
Supplier Page from
Cayman Chemical for
ZCL 278
Request Info
Description
A cell-permeable inhibitor of Cdc42, blocking interaction with the GEF intersectin; exhibits antiviral activity by blocking cellular entry and inhibiting viral replication
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
ZCL 278
Company
Cayman Chemical
Price
$77.00
Supplier Page
View Company Product Page
Catalog Number
14849
Format
A crystalline solid
Research Area
Cell Biology, Cell Cycle, Cell Signaling, GTPases, Immunology & Inflammation, Infectious Disease, Neuroscience, Viral Diseases
Molecular Weight
584.9
Quantity
10 mg
Purity
≥95%
Storage
-20
Formula
C21H19BrClN5O4S2
Origin
CHN
Type
Inhibitors
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (4)
(1)
Leukocyte-epithelial physical contacts mediate interstitial migration in vivo
ResearchSquare
February 5, 2026
Jonathan H. Huttenlocher, Jonathan Robertson, Tanner Robertson, Jack J. Stevens, Clyde W. Stevens, Clyde Tinnen, Julie Rindy, Emilie Rochon, David J. Rochon, David Huttenlocher
small molecule
inhibitors
were used at the listed final concentrations: ZCL278 (50 μm,
Cayman chemical
14849
) to
inhibit
Cdc4244,
Cytochalasin D
(5 μM,
Sigma Aldrich
C8273
) to
inhibit
actin polymerization, and
(2)
Epstein-Barr virus induces aberrant B cell migration and diapedesis via FAK-dependent chemotaxis pathways
Nat Commun
May 19, 2025
Susanne Delecluse, Francesco Baccianti, Manon Zala, Alina Steffens, Carolin Drenda, Daniel Judt, Tim Holland-Letz, Remy Poirey, Pierre Sujobert, Henri-Jacques Delecluse
at 50 μM, Y27632 (ROCK Inhibitor,
10005583
,
Cayman Chemical
, USA) at 5 μM, ZCL278 (
CDC42
Inhibitor
,
14849
,
Cayman Chemical
, USA) at 50 μM, LFA-1
Inhibitor
BIRT377 (30112547, ThermoFisherScientific, Germany)
(3)
Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence
iScience
June 21, 2024
Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata
,
Cayman Chemical Company
,Cat#
18496
EHop-016
,
Cayman Chemical Company
,Cat#
21557
ZCL-278
,
Cayman Chemical Company
,Cat#
14849
CASIN
,
Cayman Chemical Company
,Cat#
17694
Ketorolac
,
Cayman Chemical Company
,Cat#
9001148
Brefeldin A,
Cayman Chemical Company
(4)
Designing Single-Component Optogenetic Membrane Recruitment Systems: The Rho-Family GTPase Signaling Toolbox
ACS Synthetic Biology
January 21, 2022
Erin E. Berlew, Keisuke Yamada, Ivan A. Kuznetsov, Eleanor A. Rand, Chandler C. Ochs, Zaynab Jaber, Kevin H. Gardner, Brian Y. Chow
to imaging at the following concentrations and timepoints: Cdc42
inhibitor
ZCL 278
(
Cayman Chemical
,
14849
), 7.5 μM, 2 hours prior to imaging; Rac1 GEF
inhibitor
NSC 23766 (
Cayman Chemical
,
13196
), 50 μM, 24
<<
<
>
>>
Reviews
Be the First to Write a Review!
ZCL 278 from Cayman Chemical
Supplier Page
View Company Product Page
$77.00
Product Specs
Company Info
Citations
Reviews
Back To Top