Dermorphin (acetate) from Cayman Chemical

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Cayman Chemical for
Dermorphin (acetate)

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Description

An opioid peptide; binds to µ-opioid receptors (Ki = 0.54 nM) and is selective for µ- over δ-opioid receptors in radioligand binding assays (Ki = 929 nM); inhibits noxious stimuli-induced neuronal firing in the nucleus lateralis anterior and ventrobasal complex in rats at 1.9 µmol/kg; inhibits the electrical stimulation-induced C fiber response in rat dorsal horn nociceptive neurons; delays gastric emptying, inhibits gastric acid secretion, and slows colonic motility in pylorus-ligated rats from 10-120 pmol/animal