Description
A lignan with diverse biological activities; inhibits polymerization of isolated chicken brain tubulin (IC50 = 0.6 µM); induces mitotic arrest at the G2/M phase in CCRF CEM cells from 0.01 to 5 µg/ml; is protective against HSV-1 infection in Vero cells at 5 µM; inhibits proliferation of several DLBCL cell lines (IC50s = 0.0098-0.017 µM); a starting material in the semisynthesis of etoposide and teniposide