GLS1 Inhibitor from Cayman Chemical

An inhibitor of GLS1 (IC50 = 0.021 µM); inhibits the growth of NCI H1703 NSCLC cells in vitro (GI50 = 0.011 µM); reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model at 100 mg/kg