Description
An inhibitor of DGK (IC50 = 2.8 µM), increasing DAG-dependent PKC activity; blocks vascular contraction induced by U-46619 (Item No. 16450); induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells; inhibits A. thaliana DGK2 (IC50 = 50 µM) and suppresses root growth but does not affect DGK7 at 50 µM