Description
A TRPML1 agonist; induces cytosolic calcium increases in HEK293T cells expressing surface-expressed mutant TRPML1 channels at 10 µM; activates TRPML1-mediated current (IML1) in isolated vacuoles that were enlarged by vacuolin-1 prior to isolation from HEK293 cells expressing TRPML1; activates whole-endolysosome IML1 in primary murine macrophages