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Protein Biochemistry
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2-Hydroxypropyl-β-cyclodextrin
2-Hydroxypropyl-β-cyclodextrin from Cayman Chemical
Be the first to write a review!
Citations:
(14)
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Cayman Chemical for
2-Hydroxypropyl-β-cyclodextrin
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Description
A cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
2-Hydroxypropyl-β-cyclodextrin
Company
Cayman Chemical
Price
$269.00
Supplier Page
View Company Product Page
Catalog Number
16169
Format
A crystalline solid
Molecular Weight
1541.6
Quantity
25 g
Purity
≥95%
Origin
CHN
Formula
(C6H9O5)7(C3H7O)
Storage
22
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (14)
(1)
Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity
Ferroptosis and Oxidative Stress
December 29, 2025
Eduard Reznik, Fereshteh Zandkarimi, Joleen M. Csuka, Qiulin Zhu, Jenny Jin, Taruna Vani Neelakantan, Jiewen Zheng, Vasiliki Polychronidou, Mark Fongheiser, Ashley Brown,
et al.
re-dissolved in vehicle containing 20% ethanol and 16%
2-hydroxypropyl-β-cyclodextrin
(
Cayman Chemical
, #
16169
) in PBS to prepare a 30 mM solution, and sonicated until the solution was clear. Phospholipids were
(2)
Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons
bioRxiv
September 11, 2025
Chuyu Chen, Qianzi He, Giulia Tombesi, Eve Napier, Matthew Jaconelli, Oscar Andrés Moreno-Ramos, Hannah Serio, Yahaira Naaldijk, Vanessa Promes, Amanda Schneeweis,
et al.
protein",MLi-2,"
Abcam
,
ab254528
", "Chemical, peptide, or recombinant protein",Hydroxypropyl-β-Cyclodextrin,"
Cayman
,
16169
", "Chemical, peptide, or recombinant protein",
Sodium chloride solution
,"
Sigma-Aldrich
, S5150", "Chemical,
(3)
Organ of Corti macrophages: a distinct group of cochlear macrophages with potential roles in supporting cell degeneration and survival
Frontiers in Immunology
June 25, 2025
Mengxiao Ye, Celia Zhang, Dalian Ding, Guang-Di Chen, Henry J. Adler, Rania Sharaf, Bo Hua Hu
ototoxicity
2-Hydroxypropyl-β-cyclodextrin
(referred to as cyclodextrin throughout this manuscript;
Cayman Chemical Company
, Cat #
16169
, Ann Arbor, MI, USA) was freshly prepared using normal saline and administered as a single
subcutaneous injection
(4)
Supporting cell involvement in cochlear damage and repair: Novel insights from a quantitative analysis of cyclodextrin-induced ototoxicity in mice
Hearing Research
April 1, 2025
Dalian Ding, Guang Di Chen, Celia Zhang, Mengxiao Ye, Henry J. Adler, Rania Sharaf, Kayla Naldrett, Tanisi Mittal, Bo Hua Hu
(referred to as cyclodextrin throughout this manuscript) was purchased from
Cayman Chemical Company
(Cat #:
16169
, Ann Arbor, MI, USA). The solution was freshly prepared using normal saline and administered as a single
(5)
Microfluidics in Assessing Platelet Function
Journal of Visualized Experiments
November 8, 2024
Emily Mihalko, Abiha Abdullah, Lara Hoteit, David Akinbode, Susan Shea, Matthew D. Neal
Connectors,Qosina,11691, 10 mL syringe,Fischer Scientific,14-955-459,
2-Hydroxypropyl-β-cyclodextrin
,
Cayman Chemicals
,
16169
,30% Dissolved in Phosphate buffered saline 40-micron filters,
Fischer Scientific
,NC1469671,
CD41
antibody,
Novus Biologicals
(6)
LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
bioRxiv
June 13, 2024
Chuyu Chen, Meghan Masotti, Nathaniel Shepard, Vanessa Promes, Giulia Tombesi, Daniel Arango, Claudia Manzoni, Elisa Greggio, Sabine Hilfiker, Yevgenia Kozorovitskiy,
et al.
compound,drug",MLi-2,"
Abcam
,",Cat#
ab254528
"Chemical compound,drug",Hydroxypropyl-β- Cyclodextran,
Cayman
,Cat#
16169
"Chemical compound,drug",
PFE-360
,
MCE
,Cat#Y-120085 "Chemical compound,drug",hydroxypropyl cellulose,Millipore
(7)
Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis
Cell
February 29, 2024
Baiyu Qiu, Fereshteh Zandkarimi, Carla T. Bezjian, Eduard Reznik, Rajesh Kumar Soni, Wei Gu, Xuejun Jiang, Brent R. Stockwell
(
Santa Cruz Biotechnology
sc-108071A
), biotin-PEG-SH (Polypure
41156
–1095),
2-Hydroxypropyl-β-cyclodextrin
(
Cayman Chemical
16169
), 4-chlorobenzoic acid (Sigma-Aldrich 135585). The following antibodies were used: anti-
GPX4
(ab125066),
(8)
Glucagon signaling via supraphysiologic GCGR can reduce cell viability without stimulating gluconeogenic gene expression in liver cancer cells
Cancer & metabolism
February 5, 2022
Godfrey J, Riscal R, Skuli N, Simon MC.
prepared at the indicated concentration in 20%
2-hydroxypropyl-β-cyclodextrin
(
Cayman Chemical
, catalog #
16169
) pH 4.5 either as a single agent or in combination. Two hundred microliters of the drug solutions was
(9)
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis
Cell death and differentiation
August 1, 2021
Cui W, Liu D, Gu W, Chu B.
reconstituted with ethanol. The stocks were then prepared with 20% 2-hydroxypropyl-beta-cyclodextrin (
Cayman
16169
) in PBS solution. Stocks were incubated at 37 °C for 30 min and then sonicated to clear solutions at
(10)
The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area
Frontiers in Pharmacology
April 16, 2021
Hong Zhang, Austin A. Lipinski, Erika Liktor-Busa, Angela F. Smith, Aubin Moutal, Rajesh Khanna, Paul R. Langlais, Tally M. Largent-Milnes, Todd W. Vanderah
discontinued and artificial cerebral spinal fluid (aCSF) containing 10% (w/v) hydroxypropyl-β-cyclodextrin (#
16169
,
Cayman Chemical
, Ann Arbor, MI) was perfused through the
microdialysis
probe and equilibrated within
(11)
Orexin receptor antagonists reverse aberrant dopamine neuron activity and related behaviors in a rodent model of stress-induced psychosis
Translational psychiatry
February 8, 2021
Elam HB, Perez SM, Donegan JJ, Lodge DJ.
USA) were made fresh daily and dissolved in 10% DMSO and 10% 2-hydroxypropyl-b-cyclodextrin (Item No.
16169
;
Cayman Chemical
, Ann Arbor, MI, USA) in sterile water.
Chloral hydrate
and DMSO were purchased from
(12)
Testosterone metabolites differentially regulate obesogenesis and fat distribution
Molecular metabolism
February 1, 2021
Sebo ZL, Rodeheffer MS.
(DURECT Corporation #0002612). Vehicle was 45% w/v
2-hydroxypropyl-β-cyclodextrin
(
Cayman Chemical
#
16169
) in 1X PBS or 45% w/v
2-hydroxypropyl-β-cyclodextrin
(Cayman Chemical #
16169
) in 1X PBS + 10% DMSO (
Sigma Aldrich
(13)
Serine Catabolism Feeds NADH when Respiration Is Impaired
Cell metabolism
April 7, 2020
Yang L, Garcia Canaveras JC, Chen Z, Wang L, Liang L, Jang C, Mayr JA, Zhang Z, Ghergurovich JM, Zhan L,
et al
.
A2056
Thiamine pyrophosphate,Fisher,Cat# T10835G 2-hydroxypropyl-cyclodextrin,
Cayman Chemicals
,Cat#
16169
Matrigel,
Corning
,Cat#
354234
HT Supplement,Thermo Fisher Scientific,Cat# 11067–030 Sodium Pyruvate,
Gibco
,Cat#
(14)
Development of an Orthotopic Intrasplenic Xenograft Mouse Model of Canine Histiocytic Sarcoma and Its Use in Evaluating the Efficacy of Treatment with Dasatinib
Comparative Medicine
February 6, 2019
Marilia Takada, Lauren A Smyth, Jeremy ML Hix, Sarah M Corner, Sandrao'reilly, Matti Kiupel, Vilma Yuzbasiyan-Gurkan
either dasatinib (30 mg/kg IP; catalog no.
11498
,
Cayman
) or vehicle (10% β-cyclodextrin, catalog no.
16169
,
Cayman
). The dasatinib
treatment protocol
was based on a previous study,9 where 30 mg/kg IP was well
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2-Hydroxypropyl-β-cyclodextrin from Cayman Chemical
Supplier Page
View Company Product Page
$269.00
Product Specs
Company Info
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