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IKK2 Inhibitor VI
IKK2 Inhibitor VI from Cayman Chemical
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Citations:
(3)
Supplier Page
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Cayman Chemical for
IKK2 Inhibitor VI
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Description
A potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM); used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
IKK2 Inhibitor VI
Company
Cayman Chemical
Price
$70.00
Supplier Page
View Company Product Page
Catalog Number
17276
Format
A crystalline solid
Research Area
Autoimmunity, Cell Biology, Cell Signaling, Epigenetics, Transcription, & Translation, Immunology & Inflammation, Infectious Disease, Innate Immunity, NF-κB Signaling, Pattern Recognition, STING, Transcription Factors
Molecular Weight
261.3
Quantity
500 µg
Purity
≥95%
Storage
-20
Formula
C12H11N3O2S
Origin
USA
Type
Inhibitors
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
Mechanisms of HIV Latency in Hematopoietic Progenitors: GFI1 as a Key Regulator
bioRxiv
February 24, 2026
Jackline A. Onyango, Chen Li, Cuie Chen, W Miguel Disbennett, Maria C. Virgilio, Mark M. Painter, Valeri H. Terry, Barkha Ramnani, Joshua D. Welch, Kathleen L. Collins
NF-κB activation, cells were co-treated with an IKK
inhibitor
(
IKK2 inhibitor VI
,
Cayman Chemical
, cat#
17276
). Treatment concentrations and timing are provided in the figure panels. Combination LRA treatment CEM-A2
(2)
Induction, amplification, and propagation of diabetic retinopathy-associated inflammatory cytokines between human retinal microvascular endothelial and Müller cells and in the mouse retina
Cellular Signalling
December 1, 2024
Dolly Ann Padovani-Claudio, Monica S. Morales, Taylor E. Smith, Cayla D. Ontko, Neeraj S. Namburu, Samuel A. Palmer, Marvarakumari G. Jhala, Carla J. Ramos, Megan E. Capozzi, Gary W. McCollum,
et al.
dimethyl sulfoxide (DMSO
) #
D8418
,
Sigma Aldrich
] or 5 μM of the NFκB signaling
inhibitor
IKK2i-VI (#
17276
,
Cayman
; Ann Arbor, MI, USA). Vehicle (0.1 % BSA), 1 ng/mL IL-1β or 1 ng/mL TNFα were then added for
(3)
MALT1 Protease Plays a Dual Role in the Allergic Response by Acting in Both Mast Cells and Endothelial Cells
Journal of immunology (Baltimore, Md. : 1950)
May 1, 2020
Alfano DN, Klei LR, Klei HB, Trotta M, Gough PJ, Foley KP, Bertin J, Sumpter TL, Lucas PC, McAllister-Lucas LM.
N-acetyl-b-D-glucosaminide (N9376; Sigma-Aldrich), mepazine (
5.00500.0001
;
EMD
), and
IKK-2 inhibitor VI
(IKK-VI) (
17276
;
Cayman Chemical
).
Bone
marrow–derived
mast cell
culture and FACS analysis
Mast cells
were derived
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IKK2 Inhibitor VI from Cayman Chemical
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$70.00
Product Specs
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