Description
An antibiotic that has activity against Gram-positive bacteria via inhibition of WalR (MICs = 0.39 and 3.13 µg/ml for B. subtilis and S. aureus, respectively); inhibits WalR-induced repression of EGFP signaling in a reporter assay in a concentration-dependent manner; alters expression of WalR regulon genes, decreasing ydjM, yocH, and ycvE and increasing yoeB and yjeA expression in B. subtilis; halts transcription of isaA and ssaA in S. aureus