Description
An IL-4 inhibitor; binds to IL-4 (Kd = 1.8 µM); inhibits IL-4 activity in a cell-based reporter assay (EC50 = 1.81 µM); selective for IL-4 over IL-13 (EC50 = 18.2 µM); inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50 = 3.1 µM)