CBFβ Inhibitor from Cayman Chemical

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Cayman Chemical for
CBFβ Inhibitor

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Description

A small molecule that binds to CBFβ and inhibits its association with Runx1 (IC50 = 3.2 µM); blocks CBFβ-Runx1 interactions in ME-1 cells, acute myeloid leukemia cells harboring dysfunctional CBF, reducing proliferation without toxicity