TMB Substrate from Cell Signaling Technology

Product Specs
ItemTMB Substrate
CompanyCell Signaling Technology
Price $77.00 Inquire
Catalog Number7004P4
Quantity50 ml
ApplicationsELISA
Research AreaRelated Products

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Divalent siRNA for prion diseaseNucleic Acids ResApril 24, 2026Juliana E Gentile, Taylor L Corridon, Fiona E Serack, Dimas Echeverria, Zachary C Kennedy, Corrie L Gallant-Behm, Matthew R Hassler, Garth A Kinberger, Margaret N Kelemen, Nikita G Kamath, et al.followed by streptavidin–horseradish peroxidase (Thermo Fisher Scientific, 21130) and TMB (Cell Signaling, 7004P4). Our calibrator curve from 5 ng/ml to 0.05 ng/ml utilized recombinant full-length mouse PrP (MoPrP23-231)

(2) Phenotypic screening for small molecules that lower PrP in cultured cellsbioRxivApril 9, 2026Jeannine A Frei, Andrew G Reidenbach, Leo Mh Xu, Raja Mohan Gopalakrishnan, Dominick Casalana, Daniel A Sprague, Mark-Anthony Bray, Amy Q. Wang, Vanessa Laversenne, Brian Erickson, et al.High Sensitivity, 21130, Thermo Fisher Scientific, USA) for 30 minutes followed by addition of TMB (7004P4, Cell Signaling Technology, USA). The reaction was stopped by adding stop solution (Cat#) and the plate

(3) Divalent siRNA for prion diseasebioRxivMarch 5, 2026Juliana E Gentile, Taylor L Corridon, Fiona E Serack, Dimas Echeverria, Zachary C Kennedy, Corrie L Gallant-Behm, Matthew R Hassler, Garth A. Kinberger, Margaret N Kelemen, Nikita G Kamath, et al.detection, followed by streptavidin-HRP (Thermo Fisher Scientific, 21130) and TMB (Cell Signaling, 7004P4). Our calibrator curve from 5 ng/mL to 0.05 ng/mL utilized recombinant full-length mouse PrP (MoPrP23–231)

(4) Optimization of a synoviocyte-targeted biologic for inflammatory arthritis in combination or bispecific administration with TNF inhibitorsJCI InsightNovember 10, 2025Sterling H. Ramsey, Zixuan Zhao, Megan C. Lee, Thales Hein da Rosa, Ava C. Schneider, Miriam Bollmann, Nour Dada, Katie E. Frizzi, May M. Han, Jaeyeon Kim, et al.blocking buffer for 1 hour at room temperature. We added 3,3′,5,5′-Tetramethylbenzidine (TMB) substrate (7004P4; CST) for 20 minutes, followed by addition of STOP solution (7002P4; CST). Wells were washed with Tris-buffered

(5) In vivo base editing extends lifespan of a humanized mouse model of prion diseaseNature MedicineJanuary 14, 2025Meirui An, Jessie R. Davis, Jonathan M. Levy, Fiona E. Serack, John W. Harvey, Pamela P. Brauer, Catherine P. Pirtle, Kiara N. Berríos, Gregory A. Newby, Wei-Hsi Yeh, et al.followed by streptavidin-HRP (Thermo Fisher Scientific, cat. no. 21130) and TMB (Cell Signaling, cat. no. 7004P4). The standard curve was recombinant mouse PrP (MoPrP23-231) generated in-house61. The assay is validated

(6) Brain-wide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editorScienceJune 28, 2024Edwin N. Neumann, Tessa M. Bertozzi, Elaine Wu, Fiona Serack, John W. Harvey, Pamela P. Brauer, Catherine P. Pirtle, Alissa Coffey, Michael Howard, Nikita Kamath, et al.streptavidin-HRP (Pierce High Sensitivity, 21130, Thermo Fisher Scientific, USA) and TMB substrate (7004P4, Cell Signaling Technology, USA). Recombinant mouse PrP (MoPrP23-231) prepared as described (115) was

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TMB Substrate from Cell Signaling Technology

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TMB Substrate from Cell Signaling Technology

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