dTAG-13 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemdTAG-13
CompanyTocris Bioscience, a Bio-Techne Brand
Price $597.00Supplier Page View Company Product Page
Catalog Number6605/5
Quantity5 mg
Purity98%
Molecular Weight1049.18
Molecule Name1-[(2S)-1-Oxo-2-(3,4,5-trimethoxyphenyl)butyl]-(2S)-2-piperidinecarboxylate (1R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester
FormulaC57H68N4O15
StorageStore at -20°C

Specifications/Features

Sizes Available: 5 mg

Add to Compare List

Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elementseLifeFebruary 3, 2026Andria Koulle, Oluwaseun Ogundele, Devina Shah, India Baker, Maya Lopez, David Lando, Nicola Reynolds, Ramy Ragheb, Ernest D Laue, Brian Hendrich,NEBNext High-Fidelity 2X PCR Master Mix,New England Biolabs,M0541L, "Chemical compound, drug",dTAG-13,Bio-Techne Ltd,6605/5,(500 nM) "Chemical compound, drug",Auxin,Cambridge Bioscience,16954-1g-CAY,(500 µM) "Chemical compound,

(2) The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elementsElifeFebruary 3, 2026Andria Koulle, Oluwaseun Ogundele, Devina Shah, India Baker, Maya Lopez, David Lando, Nicola Reynolds, Ramy Ragheb, Ernest D Laue, Brian Hendrich,NEBNext High-Fidelity 2X PCR Master Mix,New England Biolabs,M0541L, "Chemical compound, drug",dTAG-13,Bio-Techne Ltd,6605/5,(500 nM) "Chemical compound, drug",Auxin,Cambridge Bioscience,16954-1g-CAY,(500 µM) "Chemical compound,

(3) The intrinsically disordered region of eIF5B stimulates IRES usage and nucleates biological granule formationCell reportsOctober 31, 2023Harris MT, Marr MT 2nd.solution,MilliporeSigma,11070–73-8 Effectene,Qiagen,301425 DFHBI-1T,MilliporeSigma,1539318–36-9 JetPrime Transfection System,Polyplus,101000046 dTAG-13,Tocris Bioscience,6605/5 dTAGV-1,Tocris Bioscience,6914/5 D-Sorbitol,Fisher,AA3640436 Sodium Arsenite,Fisher,714216 Vaccinia

(4) MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcomaJCI insightJuly 10, 2023Nirala BK, Patel TD, Kurenbekova L, Shuck R, Dasgupta A, Rainusso N, Coarfa C, Yustein JT.

(5) CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expressionNature communicationsJune 3, 2023Noviello G, Gjaltema RAF, Schulz EG.

(6) Loop stacking organizes genome folding from TADs to chromosomesMolecular CellMay 1, 2023Antonina Hafner, Minhee Park, Scott E. Berger, Sedona E. Murphy, Elphège P. Nora, Alistair N. Boettigerproteins" Indole – 3 – acetic acid sodium salt (auxin analog),Sigma-Aldrich,i2886 dTAG-13,Fisher,Tocris 6605/5 TCO-PEG4-TFP Ester,Click Chemistry Tools,1398–2 Methyltetrazine-PEG4-Amine,Click Chemistry Tools,1012–100 Methyltetrazine-NHS

(7) Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid LeukemiaCancer discoveryMarch 1, 2023Wang XQD, Fan D, Han Q, Liu Y, Miao H, Wang X, Li Q, Chen D, Gore H, Himadewi P, et al.considered as gained or lost regions. dTAG-13 Treatment dTAG-13 (500 nmol/L–1 μmol/L; R&D Systems, 6605/5) was added to culture media with the indicated duration described in the text. Wash-off in Fig. 3 was

(8) Optimized M24B Aminopeptidase Inhibitors for CARD8 Inflammasome ActivationJournal of medicinal chemistryFebruary 23, 2023Chen Q, Wang A, Covelli DJ, Bhattacharjee A, Wang Q, Orth-He EL, Rao SD, Huang HC, Ball DP, Hsiao JC, et al.3719), bestatin methyl ester (MeBs; Sigma, 200485), apstatin (SCBT, sc-201309), dTAG-13 (R&D Systems, 6605/5), and FuGENE HD (Promega, E2311). Reactions were monitored by thin-layer chromatography (TLC) carried

(9) Protein folding stress potentiates NLRP1 and CARD8 inflammasome activationCell reportsJanuary 31, 2023Orth-He EL, Huang HC, Rao SD, Wang Q, Chen Q, O'Mara CM, Chui AJ, Saoi M, Griswold AR, Bhattacharjee A, et al.

(10) Engineered PROTAC-CID Systems for Mammalian Inducible Gene RegulationJournal of the American Chemical SocietyJanuary 25, 2023Ma D, Yuan Q, Peng F, Paredes V, Zeng H, Osikpa EC, Yang Q, Peddi A, Patel A, Liu MS, et al.inductive small molecules, including Rapamycin (STEM CELL technologies no. 73362), dTAG-13 (TOCRIS no. 6605/5), dTAGV-1 (TOCRIS no. 6744-5), dBRD9 (TOCRIS no. 6606/5), dTRIM24 (TOCRIS no. 6607/5), MZ1 (TOCRIS no.

(11) Regulation of cohesin-mediated chromosome folding by PDS5 in mammalsEMBO reportsNovember 7, 2022Yu D, Chen G, Wang Y, Wang Y, Lin R, Liu N, Zhu P, Liu H, Hu T, Feng R, et al.

(12) The histone methyltransferase SETD2 negatively regulates cell sizeJournal of cell scienceOctober 1, 2022Molenaar TM, Malik M, Silva J, Liu NQ, Haarhuis JHI, Ambrosi C, Kwesi-Maliepaard EM, van Welsem T, Baubec T, Faller WJ, et al.

(13) Systematic profiling of conditional degron tag technologies for target validation studiesNature communicationsSeptember 20, 2022Bondeson DP, Mullin-Bernstein Z, Oliver S, Skipper TA, Atack TC, Bick N, Ching M, Guirguis AA, Kwon J, Langan C, et al.

(14) Generation of knock-in degron tags for endogenous proteins in mice using the dTAG systemSTAR protocolsSeptember 16, 2022Abuhashem A, Hadjantonakis AK.

(15) A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasomeThe Journal of biological chemistryJuly 1, 2022Hsiao JC, Neugroschl AR, Chui AJ, Taabazuing CY, Griswold AR, Wang Q, Huang HC, Orth-He EL, Ball DP, Hiotis G, et al.

(16) A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalencyCell reportsJune 7, 2022Huang X, Bashkenova N, Hong Y, Lyu C, Guallar D, Hu Z, Malik V, Li D, Wang H, Shen X, et al.

(17) NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modesNucleic acids researchMay 20, 2022Bao H, Carraro M, Flury V, Liu Y, Luo M, Chen L, Groth A, Huang H.

(18) Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1Cell reportsMay 17, 2022Bowness JS, Nesterova TB, Wei G, Rodermund L, Almeida M, Coker H, Carter EJ, Kadaster A, Brockdorff N.

(19) BRD2 compartmentalizes the accessible genomeNature geneticsApril 1, 2022Xie L, Dong P, Qi Y, Hsieh TS, English BP, Jung S, Chen X, De Marzio M, Casellas R, Chang HY, et al.

(20) Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)Blood cancer journalJanuary 11, 2022Fiskus W, Boettcher S, Daver N, Mill CP, Sasaki K, Birdwell CE, Davis JA, Takahashi K, Kadia TM, DiNardo CD, et al.

Be the First to Write a Review!

dTAG-13

dTAG-13 from Tocris Bioscience, a Bio-Techne Brand

Description

Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (26)

Reviews

dTAG-13 from Tocris Bioscience, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map