Recombinant Human Fc gamma RIIIA/CD16a (V176F) Protein, CF 8894-FC-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Fc gamma RIIIA/CD16a (V176F) Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $454.00Supplier Page View Company Product Page
Catalog Number8894-FC-050
Size50 ug
FormatLyophilized from a 0.2 µm filtered solution in sterile PBS
Molecular WeightObserved: 43-58 kDa, reducing conditions
Theoretical: 23 kDa
SpeciesHuman
Molecule NameFc gamma RIIIA/CD16a
Source/Expression SystemHEK293-derived Recombinant Human Fc gamma RIIIA/CD16a (V176F) Protein, CF
NCBI Full Gene NameFc gamma receptor IIIa
NCBI Gene AliasesCD16-II, FCRIIIA, FCR-10, FCRIII, FCG3, FCGRIII, CD16, FcGRIIIA, IMD20, CD16A, IGFR3, FCGR3
ApplicationsBioactivity
Conjugate/TagUnconjugated
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platformDrug DelivMay 26, 2025Barnabas Nyesiga, Karin Hägerbrand, Laura Varas, Anette Gjörloff Wingren, Mats Ohlin, Peter Ellmark, Laura von SchantzR&D Systems), FcγRIIb (1875-CD-050, R&D Systems), FcγRIIIa-V176 (4325-FC-050, R&D Systems), FcγRIIIa F176 (8894-FC-050, R&D Systems), or mouse FcγRI (2074-FC, R&D Systems), FcγRIIb (1460-CD, R&D Systems), FcγRIII (1960-FC,

(2) Specific location of galactosylation in an afucosylated antiviral monoclonal antibody affects its FcÎ³RIIIA binding affinityFrontiers in ImmunologyOctober 12, 2022Grayson Hatfield, Lioudmila Tepliakova, Genevieve Gingras, Andrew Stalker, Xuguang Li, Yves Aubin, Roger Y. Tamaffinity, R&D Systems, Cat# 4325-FC-050), or at 0.67 µg/mL for FcγRIIIA V176F (low affinity, R&D, Cat# 8894-FC-050). Following washing with 0.05% Tween 20 in PBS pH 7.4 (PBS-T) and blocking with 1% bovine serum albumin

(3) Discovery of a novel Igβ and FcγRIIB cross-linking antibody, ASP2713, and its potential application in the treatment of systemic lupus erythematosusInternational immunopharmacologyDecember 1, 2021Kitanaga Y, Yamajuku D, Kubo S, Nakamura K, Maeda M, Seki M, Kaneko Y, Kinugasa F, Morokata T, Kondo Y, et al.

(4) Extending human IgG half-life using structure-guided designmAbsJuly 26, 2018Brian J. Booth, Boopathy Ramakrishnan, Kristin Narayan, Andrew M. Wollacott, Gregory J. Babcock, Zachary Shriver, Karthik ViswanathanV176, and IIIa F176 (R&D Systems catalog # 1257-FC-050, 1330-CD-050, 1875-CD-050, 4325-FC-050, and 8894-FC-050, respectively) was measured by ELISA. All Fc variants were tested in the context of the motavizumab,

(5) Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune DiseaseJournal of immunology (Baltimore, Md. : 1950)February 1, 2016Zhang X, Olsen HS, Chen S, So E, Zhou H, Burch E, Mérigeon EY, Block DS, Strome SE.

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Fc gamma RIIIA/CD16a V176F Polymorphic Variant Protein

Fc gamma RIIIA/CD16a V176F Polymorphic Variant Protein

Fc gamma RIIIA/CD16a V176F Polymorphic Variant Protein

Recombinant Human Fc gamma RIIIA/CD16a (V176F) Protein, CF from R&D Systems, a Bio-Techne Brand

Description

R&D Systems, a Bio-Techne Brand

Citations (5)

Reviews

Recombinant Human Fc gamma RIIIA/CD16a (V176F) Protein, CF from R&D Systems, a Bio-Techne Brand

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