Description
Description: CNTF is a survival factor for various neuronal cell types. seems to prevent the degeneration of motor axons after axotomy. Image: CNTF protein structure and sequence References: 1. Ciliary neurotrophic factor is not required for terminal sprouting and compensatory reinnervation of neuromuscular synapses: re-evaluation of CNTF null mice. Exp Neurol 2007 Jun;205(2):437-482. Use of suppression subtractive hybridization to identify genes regulated by ciliary neurotrophic factor in postnatal retinal explants. Mol Vis 2007 Feb 7;13:206-193. Molecular and cellular alterations induced by sustained expression of ciliary neurotrophic factor in a mouse model of retinitis pigmentosa. Invest Ophthalmol Vis Sci 2007 Mar;48(3):1389-4004. Intravitreal injection of ciliary neurotrophic factor (CNTF) causes peripheral remodeling and does not prevent photoreceptor loss in canine RPGR mutant retina. Exp Eye Res 2007 Apr;84(4):753-715. Activation of GABA(A) receptors facilitates astroglial differentiation induced by ciliary neurotrophic factor in neural progenitors isolated from fetal rat brain. J Neurochem 2007 Mar;100(6):1667-796. Regulation of rod phototransduction machinery by ciliary neurotrophic factor. J Neurosci 2006 Dec 27;26(52):13523-30