Description
Leucine-Rich Repeat Neuronal Protein 1 (LRRN1) is a member of the neuronal LRR family. Human LRRN1 is synthesized as a 683 amino acid protein that contains one CH (calponin-homology) domain and nine LRR (leucine-rich) repeats. LRRN1 is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. The calponin homology (CH) domain is suggested to confer actin binding to a variety of cytoskeletal and signaling molecules. Identified structural elements suggest that LRRN1 resembles a receptor