Recombinant Human ACVR2B, Fc tagged ACVR2B-196H from Creative BioMart

Product Specs
ItemRecombinant Human ACVR2B, Fc tagged
CompanyCreative BioMart
Price Supplier Page View Company Product Page
Catalog NumberACVR2B-196H
NCBI Full Gene Nameactivin A receptor type 2B
NCBI Gene AliasesACTRIIB, ActR-IIB, HTX4
Molecular WeightThe recombinant human ACVR2B/Fc chimera is a disulfide-linked homodimer generated after removal of the signal peptide. The reduced monomer comprises 354 amino acids and predicts a molecular mass of 40.0 kDa. As a result of glycosylation, the monomer migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions
Gene NameACVR2B, Fc tagged (Human)
ApplicationsFor research and further manufacturing use
Size1
Purity>90 % as determined by SDS-PAGE
Activity1. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.02-0.1 µg/mL in the presence of 10 ng/mL recombinant Activin A. 2. Measured by its binding ability in a functional ELISA. Immobilized Inhibin Human, Mouse, Rat, Cynomolgus, Rhesus Inhibin beta A/Activin A at 2 µg/ml (100 µl/well) can bind Human ACVR2B hFc, the EC50 of Human ACVR2B hFc is 12-60 ng/mL
Conjugate/TagFc
Molecule NameACVR2B
Source/Expression SystemHuman Cells
SpeciesHuman

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Recombinant Human ACVR2B, Fc tagged from Creative BioMart