Recombinant Rat Acvrl1, Fc-His tagged Acvrl1-245R from Creative BioMart

Product Specs
ItemRecombinant Rat Acvrl1, Fc-His tagged
CompanyCreative BioMart
Price Supplier Page View Company Product Page
Catalog NumberAcvrl1-245R
SpeciesRat
Source/Expression SystemHuman Cells
Gene NameAcvrl1, Fc-His tagged (Rat)
Molecule NameAcvrl1
Conjugate/TagFc, His
NCBI Full Gene Nameactivin A receptor like type 1
NCBI Gene AliasesAlk1, R-3, R3, SETHKIR
ApplicationsFor research and further manufacturing use
Molecular WeightThe secreted recombinant rat ACVRL1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 343 amino acids with a predicted molecular mass of 38.7 kDa. As a result of glycosylation, it migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions
Size1
Purity>90 % as determined by SDS-PAGE
ActivityMeasured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953.The ED50 for this effect is typically 40-200 ng/mL in the presence of 2 ng/mL of recombinant human BMP9

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Recombinant Rat Acvrl1, Fc-His tagged from Creative BioMart