Description
Putative Acyl-Coenzyme A Thioesterase 6 (ACOT60 is a member of the C/M/P thioester hydrolase family. It has been revealed by sequence analysis that ACOT6 consists of a putative peroxisomal targeting signal at the C-terminal end. Cellular localization experiments show that it serves as a peroxisomal enzyme. Otherwise, ACOT6 has been identified as a target gene of the peroxisome proliferator-activated receptor alpha (PPARα) and is up-regulated in mouse liver in a PPARα-dependent manner