Description
IL4 is a pleiotropic cytokine produced by activated T cells. It participates in several B-cell activation processes as well as of other cell types. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1, as well as regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. In addition, it is a costimulator of DNA-synthesis