Description
Adenylyltransferase and Sulfurtransferase MOCS3 (MOCS3) is a member of the hesA/moeB/thiF family. MOCS3 contains one Molybdopterin-synthase adenylyltransferase domain and one Molybdopterin-synthase sulfurtransferase domain. MOCS3 plays an important role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln), MOCS3 is essential for biosynthesis of the molybdenum cofactor. MOCS3 can interact with NFS1, which may act as a sulfur donor for thiocarboxylation reactions