Recombinant Mouse Fcgr1, His tagged Fcgr1-2279M from Creative BioMart

Product Specs
ItemRecombinant Mouse Fcgr1, His tagged
CompanyCreative BioMart
Price Supplier Page View Company Product Page
Catalog NumberFcgr1-2279M
Size1
Conjugate/TagHis
ApplicationsFor research and further manufacturing use
Purity>90 % as determined by SDS-PAGE
Activity1. Immobilized Rituximab (IgG1) at 1 µg/mL can bind Mouse FcγRI / CD64 recombinant protein, the EC50 is 16-35 ng/mL. 2. Immobilized Anti-CD3 antibody, mouse IgG2a at 2 µg/mL (100 µL/well) can bind Recombinant Mouse CD64 / FCGR1 Protein (His Tag), the EC50 is 0.8-2.4 ng/mL. 3. Loaded Mouse FcγRI / CD64 recombinant protein on His1K Biosensor, can bind Bevacizumab (IgG1) with an affinity constant of 0.12 µM as determined in a BLI assay (Sartorius Octet Red384). 4. Loaded Mouse FcγRI / CD64 recombinant protein on His1K Biosensor, can bind Nivolumab (IgG4) with an affinity constant of 0.28 µM as determined in a BLI assay (Sartorius Octet Red384). 5. Captured Mouse FcγRI / CD64 recombinant protein on Anti-His Chip can bind Bevacizumab (IgG1) with an affinity constant of 0.12 µM as determined in an SPR assay (Biacore T200). 6. Captured Mouse FcγRI / CD64 recombinant protein on Anti-His Chip can bind Nivolumab (IgG4) with an affinity constant of 0.69 µM as determined in an SPR assay (Biacore T200) (Routinely tested). 7. The purity of Mouse CD64 / FCGR1 Protein (His Tag) is more than 95% and the molecular weight of this protein is around 40-50 kDa verified by SEC-MALS. 8. Loaded Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) on ProA Biosensor, can bind Recombinant Mouse CD64 Protein, His Tag with an affinity constant of 3.46nM as determined in BLI assay (Sartorius Octet RED384). 9. Loaded Recombinant Mouse CD16/FCGR3 Protein, His Tag on His1K Biosensor, can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) with an affinity constant of 18.5nM as determined in BLI assay (Sartorius Octet RED384)
SpeciesMouse
Source/Expression SystemHuman Cells
Gene NameFcgr1, His tagged (Mouse)
NCBI Full Gene NameFc receptor, IgG, high affinity I
Molecule NameFcgr1
Molecular WeightThe recombinant mouse FCGR1 consists of 284 amino acids after removal of the signal peptide and has a predicted molecular mass of 32 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FCGR1 is approximately 45-50 kDa due to glycosylation
NCBI Gene AliasesCD64, FcgammaRI, IGGHAFC

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Creative BioMart

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1-516-512-3133

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Recombinant Mouse Fcgr1, His tagged from Creative BioMart

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Creative BioMart

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Recombinant Mouse Fcgr1, His tagged from Creative BioMart

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