Recombinant Human FLT4, Fc tagged FLT4-889H from Creative BioMart

Product Specs
ItemRecombinant Human FLT4, Fc tagged
CompanyCreative BioMart
Price Supplier Page View Company Product Page
Catalog NumberFLT4-889H
ApplicationsFor research and further manufacturing use
Molecular WeightThe recombinant human VEGFR3/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 990 amino acids and predicts a molecular mass of 111 kDa. As a result of glycosylation and proteolytic cleavage, rhVEGFR3/Fc migrates as three bands (160, 85, 75 kDa) corresponding to the full length and the cleaved two polypeptides respectively in SDS-PAGE under reducing conditions
Size1
Purity>90 % as determined by SDS-PAGE
ActivityMeasured by its binding ability in a functional ELISA. 1. Immobilized recombinant human VEGFR3 at 5 µg/ml (100 µl/well) can bind recombinant human VEGF-D at a linear range of 62.5-2000 ng/ml. 2. Immobilized recombinant human VEGF-C at 10 µg/ml (100 µl/well) can bind recombinant human VEGFR3 at a linear range of 0.64-80 ng/ml. 3. Scatchard analysis showed the affinity constant (Kd) of recombinant human VEGF-C bound to recombinant human VEGFR3 was 1.4 nM
Conjugate/TagFc
Molecule NameFLT4
NCBI Gene AliasesCHTD7, FLT-4, FLT41, LMPH1A, LMPHM1, PCL, VEGFR-3, VEGFR3
NCBI Full Gene Namefms related receptor tyrosine kinase 4
Source/Expression SystemHuman Cells
SpeciesHuman
Gene NameFLT4, Fc tagged (Human)

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Recombinant Human FLT4, Fc tagged from Creative BioMart