Description
Product Characteristics: Please inquire for additional information about product characteristics
antibodies-online can provide customization with regards to expression system, tag location and sequence for our made to order proteins designed and produced in Germany. Please contact our customer support for further information.:
Target Information: Plays a role as a marker and a regulator of neuronal differentiation\, Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and nerve growth factor/NGFB. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. May play a role as a tumor repressor and functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1 (By similarity)