Human Tumor Necrosis Factor alpha (TNF-alpha), E Coli from MyBioSource.com

Supplier Page

Supplier Page from
MyBioSource.com for
Human Tumor Necrosis Factor alpha (TNF-alpha), E Coli

Get Pricing

Description

Description: Recombinant human TNF-alpha produced in E Coli is a single, non-glycosylated, polypeptide chain containing 157 amino acids, two pairs of disulfide bonds and having a molecular mass of approximately 17.4kD.
Introduction: Tumor necrosis factor alpha (TNFalpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction.
Human TNF-alpha is a 17.4kD factor produced by macrophages, monocytes, neutrophils, CD4+ T cells and NK cells. A 26kD form of TNF-alpha is expressed as a membrane bound molecule. TNF-alpha is cytolytic and plays an important role in immune regulation. Dimers and trimers of TNF-alpha have been observed