Description
Description: Recombinant human IL-4 produced in Yeast is a single, glycosylated, polypeptide chain containing 129 amino acids, three pairs of disulfide bonds and having a molecular mass of approximately 15.0kD (after glycosylation, the molecular mass is 30.0kD).
Introduction: Interleukin 4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). Subsequent to the molecular cloning and expression of both human and Mouse IL-4, numerous other functions have been described on B cells as well as other hematopoietic and nonhematopoietic cells, including T lymphocytes, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, endothelial cells, etc. IL-4 exhibits anti-tumor effects both in vivo and in vitro