Description
Uricase is very important for the determination of uric acid in biological fluids. Not only is the reaction specific, it may be monitored at 292nm, 340nm or colorimetrically by coupled chromogenic response. Non-enzymatic methods are interfered with by turbidity or the presence of aspirin, ascorbic acid, glutathione, paracetanol and many antibiotics.
Uricase (urate oxidase) catalyzes the overall reaction that represents the termination of purine catabolism in all mammals excluding man, higher apes and the Dalmatian dog