Description
Description: F11R Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 238 amino acids (26-238 a.a) and having a molecular mass of 25.8kDa.F11R is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: F11R (CD321) is a member of the immunoglobulin superfamily. F11R has a role in epithelial tight junction formation. Tight junctions exemplify one type of cell-to-cell adhesion in epithelial or endothelial cell sheets, establishing continuous seals around cells and acting as a physical barrier to thwart solutes and water from passing easily through the paracellular space. F11R protein can function as a receptor for reovirus, or as a ligand for the integrin LFA1, involved in leukocyte transmigration, or a platelet receptor