Recombinant Epstein-Barr virus DNA polymerase processivity factor BMRF1 (BMRF1) from MyBioSource.com

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Recombinant Epstein-Barr virus DNA polymerase processivity factor BMRF1 (BMRF1)

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Description

Plays an essential role in the viral lytic DNA replication by acting as the polymerase accessory subunit. Stimulates the viral DNA polymerase activity and appears to function with it as a holoenzyme. Increases the processivity of the viral polymerase, probably by acting as a sliding clamp that prevents dissociation of the polymerase from the active template. In addition, BMRF1 transcriptionally activates the early BHLF1 promoter