Description
Description: SPRY4 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (1-299) and having a molecular mass of 34.9 kDa.SPRY4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Sprouty Homolog 4 (SPRY4) is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. SPRY4 is positioned upstream of RAS activation. SPRY4 protein functions include suppressing the insulin receptor and EGFR-transduced MAPK signaling pathway as well as impairing the formation of GTP-Ras