Description
Description: POLE3 Human Recombinant produced in E Coli is a single polypeptide chain containing 170 amino acids (1-147) and having a molecular mass of 19kDa. POLE3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Polymerase (DNA Directed), Epsilon 3, also know as POLE3, is a histone-fold protein which interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers merge into larger enzymatic complexes for DNA transcription, replication, and packaging