Description
Recombinant human PSKH1 (2-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Scientific Background: PSKH1 is a member of the family of protein serine kinase H1 which was originally cloned by homology probing (1). PSKH1 has been localized to the endoplasmic reticulum (ER), the Golgi apparatus, and the plasma membrane (PM). PSKH1 has been shown to play a structural and regulatory role in maintenance of the Golgi apparatus, which is a key organelle within the secretory pathway. PSKH1 is in a cluster of 5 unrelated genes on 16q22.1 chromosome which is transcribed in the opposite direction from that of LCAT which is a member of the same cluster (2)