Description
The C
EBP family of transcription factors regulates viral and cellular CCAAT
enhancer element-mediated transcription. C
EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C
EBP family consist of several related proteins, C
EBP alpha, C
EBP beta, C
EBP gamma, and C
EBP delta, that form homodimers and that form heterodimers with each other. CCAAT
enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements