Description
Recombinant full-length human OSR1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Scientific Background: OSR1 is a member of the Ser/Thr family of protein kinases. OSR1 is activated by osmotic stresses and regulates the downstream protein kinase such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress (1). OSR1 can be phosphorylated by ATM or ATR during DNA damage process (2)