Description
Description: Granulocyte Colony Stimulating Factor is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. GCSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, proliferation, differentiation and function of neutrophil granulocyte progenator cells and mature neutrophils. Granulocyte Colony Stimulating Factor Mouse Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids and having a molecular mass of 19 KD. G-CSF is purified by proprietary chromatographic techniques. Image: G-CSF Mouse Structure and Sequence. References: 1. Effects of granulocyte-colony stimulating factor on peritoneal defense mechanisms and bacterial translocation after administration of systemic chemotherapy in rats. World J Gastroenterol 2007 May 14;13(18):2596-9.2. May granulocyte colony-stimulating factor induce hypercoagulable state? Am Heart J 2007 Jun;153(6):e41.3. The effect of stem cell mobilisation with granulocyte colony-stimulating factor on the morphology of the haematopoietic organs in mice. Folia Morphol (Warsz) 2007 Feb;66(1):1-9.4. Paradoxical drop in circulating neutrophil count following granulocyte-colony stimulating factor and stem cell factor administration in rhesus macaques. Exp Hematol 2007 Jun;35(6):872-8.5. Pathologic complete response with six compared with three cycles of neoadjuvant epirubicin plus docetaxel and granulocyte colony-stimulating factor in operable breast cancer: results of ABCSG-14. J Clin Oncol 2007 May 20;25(15):2012-8.6. Granulocyte colony-stimulating factor and severe aplastic anemia. Blood 2007 May 15;109(10):4589; author reply 4589-90