Description
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. This protein is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42
Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ
TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation