Recombinant Viral B18R Protein, CF 8185-BR-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Viral B18R Protein, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $321.00Supplier Page View Company Product Page
Catalog Number8185-BR-025
Size25 ug
SpeciesViral
Molecule NameB18R
Source/Expression SystemHEK293-derived Recombinant Viral B18R Protein, CF
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 80-95 kDa, reducing conditions
Theoretical: 65 kDa (monomer)
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Rewired type I IFN signaling is linked to age-dependent differences in COVID-19Cell Reports MedicineAugust 19, 2025Lev Petrov, Sophia Brumhard, Sebastian Wisniewski, Philipp Georg, David Hillus, Anna Hiller, Rosario Astaburuaga-García, Nils Blüthgen, Emanuel Wyler, Katrin Vogt, et al.proteins" ,, Staphylococcal enterotoxin B (SEB),Sigma,S4881-1MG hIFN-α 2a,Shenandoah,100–54 B18R,"R&D Systems, Biotechne",8185-BR-025 CD38 Inh_78c,"Tocris, Biotechne",6391 ,, Critical commercial assays,Critical commercial assays,Critical

(2) Innate lymphoid cells are activated in HFRS, and their function can be modulated by hantavirus-induced type I interferonsPLoS pathogensJuly 1, 2024García M, Carrasco García A, Weigel W, Christ W, Lira-Junior R, Wirth L, Tauriainen J, Maleki K, Vanoni G, Vaheri A, et al.

(3) MicroRNA-25/93 induction by Vpu as a mechanism for counteracting MARCH1-restriction on HIV-1 infectivity in macrophagesmBioOctober 31, 2023Lodge R, Xu Z, Eklund M, Stürzel C, Kirchhoff F, Tremblay MJ, Hobman TC, Cohen ÉA.inhibitor Raltegravir (Santa Cruz Biotechnology #sc-364600; 20 µM); IFN-I inhibitor B18R (R&D Systems #8185-BR-025; 50 ng/mL); β-catenin inhibitors KYA1797K (Sigma #SML1831; 10 µM) and PNU-74654 (R&D Systems #3534/5;

(4) IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cellsiScienceNovember 19, 2021Wiche Salinas TR, Gosselin A, Raymond Marchand L, Moreira Gabriel E, Tastet O, Goulet JP, Zhang Y, Vlad D, Touil H, Routy JP, et al.,R&D Systems,Cat#7955-IL-025 rhTNF-α,R&D Systems,Cat#210-TA-020 Recombinant Viral B18R Protein,R&D Systems,Cat#8185-BR-025 rhCCL20,R&D Systems,Cat#360-MP-025 ,, Critical commercial assays,Critical commercial assays,Critical

(5) Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responsesNature communicationsAugust 12, 2021Chen Q, Coto-Llerena M, Suslov A, Teixeira RD, Fofana I, Nuciforo S, Hofmann M, Thimme R, Hensel N, Lohmann V, et al.

(6) ILF3 Is a Negative Transcriptional Regulator of Innate Immune Responses and Myeloid Dendritic Cell MaturationJournal of immunology (Baltimore, Md. : 1950)June 15, 2021Nazitto R, Amon LM, Mast FD, Aitchison JD, Aderem A, Johnson JS, Diercks AH.of 70,000 cell per 150 μL in complete RPMI medium with polybrene (2 μg/mL). B18R (R&D Systems Cat: 8185-BR-025) for IFN neutralization was used for flow cytometry analysis of CD86 by adding B18R at a concentration

(7) MAIT cell activation is associated with disease severity markers in acute hantavirus infectionCell reports. MedicineMarch 16, 2021Maleki KT, Tauriainen J, García M, Kerkman PF, Christ W, Dias J, Wigren Byström J, Leeansyah E, Forsell MN, Ljunggren HG, et al.human IFN alpha A (alpha 2A),PBL assay,Cat#11100-1 Recombinant viral B18R protein,R&D Systems,Cat#8185-BR-025 BD GolgiStop™ Protein transport inhibitor (containing monensin),BD Biosciences,Cat#554724 BD GolgiPlug™

(8) MicroRNA Profiles in Monocyte-Derived Macrophages Generated by Interleukin-27 and Human Serum: Identification of a Novel HIV-Inhibiting and Autophagy-Inducing MicroRNAInternational journal of molecular sciencesJanuary 28, 2021Imamichi T, Goswami S, Hu X, Laverdure S, Yang J, Qiu J, Chen Q, Sherman BT, Chang W.

(9) Loss of the Nuclear Protein RTF2 Enhances Influenza Virus ReplicationJournal of virologyOctober 27, 2020Chia BS, Li B, Cui A, Eisenhaure T, Raychowdhury R, Lieb D, Hacohen N.mentioned above. For IFN signaling inhibition, we used recombinant viral B18R protein (catalog number 8185-BR-025; R&D Systems) and ruxolitinib (catalog number tlrl-rux; Invivogen). Baloxavir was obtained from MedChemExpress

(10) Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector ProteinsCell reportsJune 16, 2020Swaim CD, Canadeo LA, Monte KJ, Khanna S, Lenschow DJ, Huibregtse JM.HMW,InvivoGen,CAT#tlrl-pic Heat-killed S. typhimurium,InvivoGen,CAT#tlr-hkst2 Recombinant Viral B18R protein CF,R&D Systems,CAT#8185-BR-025 MYD88 inhibitor peptide,Novus,CAT#NBP2-29328 ,, Critical Commercial Assays,Critical Commercial Assays,Critical

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B18R Protein

B18R Protein

B18R Protein

Recombinant Viral B18R Protein, CF from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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Recombinant Viral B18R Protein, CF from R&D Systems, a Bio-Techne Brand

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