Description
Human Immunoglobulin M (IgM) is available in bulk quantities, from 1,000 mg single lot sizes.
Custom preparations, technical support, bulk quantities and aliquoting available.
Immunoglobulin M forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer or occasionally as a hexamer. IgM is by far the physically largest antibody in the circulation. Due to its polymeric nature, it possesses high avidity, and is particularly effective at complement activation.
IgM is the class of immunoglobulin characterized by heavy chains and is the first immunoglobulin to appear on the surface of B cells and the first to be secreted